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. 2016 Sep 1;17(7):380–385. doi: 10.1038/gene.2016.35

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Copyright © 2016 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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Child's PHA-induced cytokines over time, based on maternal or child genotypes. Only SNPs that showed significant associations in the multivariate models are shown. Error bars represent geometric means of (a) IL-10, (b) TNF-α, (c) IFN-γ and (d and e) IL-5 levels of children at the age of 2 months (T2), 5 months (T5), 12 months (T12), 24 months (T24) and 48 months (T48). Red dots/interrupted lines indicate the children having or born to mothers with major homozygote alleles, whereas black dots/solid lines for heterozygotes and blue dots and solid lines for minor homozygotes. All values were adjusted for maternal cytokines, village of residence and child's gender.