Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Dec 21;39(12):898–908. doi: 10.14348/molcells.2016.0210

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Korean Society for Molecular and Cellular Biology. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

PMC Copyright notice

Fig. 5 — Crosstalk between ITGA8 and PDGFR signaling. (A) Data for genetic and expression alterations of ITGA8 were obtained from the cBioPortal cancer genomics platform (http://www.cbioportal.org). The 877 samples of all tumors having mRNA, CNA and sequencing data were analyzed. The % on the left represents the percentage of cases with alteration. (B) The tendency of co-occurrence between ITGA8 and PDGFRA or ITGA8 and PDGFRB. (C) The relative levels of PDGFRA and PDGFRB mRNA expression were confirmed using qRT-PCR in integrin-α8 overexpressed LP1 and 8226 cells and normalized to 18s transcript. The data shown are the mean relative fold changes ± SD of three independent experiments compared to the control. Gene expression values in the samples were divided by those in the controls (i.e. each gene in the control is ‘1’).