Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 10;7:37049. doi: 10.1038/srep37049

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Western blotting for AMOT, Merlin, pYAP and LSR in AMOT-knockdown Sawano cells with and without siRNA-YAP. (b) Immunocytochemical staining for AMOT, Merlin and LSR in AMOT-knockdown Sawano cells. Scale bars: 10 μm. (c) Matrigel invasion assay of AMOT-knockdown Sawano cells with and without siRNA-YAP. Scale bars: 100 μm. The results are shown as a bar graph. Control vs. siRNA-AMOT: **p < 0.01. siRNA-AMOT vs. siRNA-AMOT + YAP: ^##p < 0.01. (d) Migration assay of AMOT-knockdown Sawano cells with and without siRNA-YAP. Scale bars: 400 μm. The results are shown as a bar graph. Control vs. siRNA-AMOT: **p < 0.01. siRNA-AMOT vs. siRNA-AMOT + YAP: ^##p < 0.01. (e) Overview of the intracellular signal mechanisms by which the loss of LSR promotes cell invasion and migration via upregulation of TEAD/AREG in human endometrial cancer cells.