Table 1. Frequency of cytogenetic abnormalities by iFISH in different subgroups.
Cytogenetic abnormalities by iFISH (N=742) | CPCs absent (n=678) | CPCs present (n=162) | P-value |
---|---|---|---|
Deletion 17p, n (%) | 65 (11.0) | 24 (15.9) | 0.107 |
t(4;14), n (%) | 43 (7.3) | 25 (16.6) | <0.001 |
t(14;16), n (%) | 22 (3.7) | 6 (4.0) | 0.883 |
t(14; 20), n (%) | 6 (1.0) | 2 (1.3) | 0.747 |
+1q, n (%) | 29 (4.9) | 8 (5.3) | 0.845 |
Deletion 13q or monosomy 13 | 244 (41.3) | 84 (55.6) | 0.002 |
Abbreviations: CPC, circulating plasma cell; iFISH, interphase fluorescence in situ hybridization; N, number of patients with available data on iFISH cytogenetics. Bold values indicate statistically significance parameters.