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. 2017 Jan 10;7:40487. doi: 10.1038/srep40487

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) The miR-214-3p level and (b) mRNA levels of TRAP and CTSK in bone specimens from breast cancer patients and cancer-free individuals with fracture (Control). (c) The correlation analysis between miR-214-3p level and TRAP (or CTSK) mRNA level in bone tissue. Note: miR-214-3p levels were normalized to U6 and osteoclast marker genes mRNA levels were normalized to Gapdh. *P < 0.05, ***P < 0.001.