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. 2017 Jan 10;7:40166. doi: 10.1038/srep40166

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This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Topology shown is based on Bennett and coworkers⁵⁹. As shown, the PNS + CNS mutants are distributed throughout the length of Cx32 while all four PNS-only mutants are located in the C-terminal half of the protein.