Skip to main content
. Author manuscript; available in PMC: 2017 Jan 10.
Published in final edited form as: J Cell Biochem. 2016 Sep 26;117(12):2815–2824. doi: 10.1002/jcb.25582

Fig. 1. GAS6 expressed by osteoblasts in bone marrow, which inhibits PCa cell proliferation and the expression of cell cycle markers.

Fig. 1

(A) GAS6 expression by osteoblasts (red, white arrows) in the bone marrow of the long bones of GAS6 expressing wild-type (GAS6+/+) mice and GAS6 deficient GAS6 knockout (GAS6−/−) mice as detected by immunofluorescence staining. Blue, DAPI nuclear stain. Bar=20μm. (B) Secretion levels of GAS6 protein in the marrow fluid of the GAS6+/+ and GAS6−/− mice as detected by ELISA. (C) The proliferation assays in PCa cells were performed by XTT. mRNA expression levels of (D) PLK1 and (E) STK15 were measured as qPCR. Data in Fig. 1B–E are representative of mean with s.d. (Student’s t-test).