Table 2.
Prognostic factors for disease-specific survival (DSS) in univariable and multivariable Cox proportional hazards regression models
| Univariate (log-rank) | Multivariate | ||||
|---|---|---|---|---|---|
| 5-year DSS (%) | p value | HR | 95% CI | p value | |
| Gender | |||||
| Male | 72.3 | ||||
| Female | 74.6 | 0.891 | |||
| Age | |||||
| <65 | 78.8 | 1 | |||
| ≥65 | 68.1 | 0.025 | 1.42 | 0.90 to 2.26 | 0.136 |
| Pathological type | |||||
| Differentiated | 82.0 | 1 | |||
| Undifferentiated | 65.4 | 0.004 | 1.32 | 0.82 to 2.12 | 0.253 |
| Main location | |||||
| Middle or lower | 76.1 | 1 | |||
| Upper | 59.7 | 0.026 | 1.52 | 0.94 to 2.47 | 0.089 |
| Depth of invasion | |||||
| T1 | 97.4 | 1 | |||
| T2-T4 | 56.0 | <0.001 | 7.66 | 2.71 to 21.6 | <0.001 |
| LN metastasis | |||||
| Negative | 94.5 | 1 | |||
| Positive | 50.0 | <0.001 | 6.40 | 3.10 to 13.2 | <0.001 |
| TPX2 | |||||
| Low | 78.1 | 1 | |||
| High | 65.9 | 0.004 | 1.05 | 0.66 to 2.26 | 0.840 |
DSS disease-free survival, TPX2 targeting protein for Xenopus kinesin-like protein 2, LN lymph node