Table 3.
Prognostic factors for relapse-free interval (RFI) in univariable and multivariable Cox proportional hazards regression models
| Univariate (log-rank) | Multivariate | ||||
|---|---|---|---|---|---|
| 5-year RFI (%) | p value | HR | 95% CI | p value | |
| Gender | |||||
| Male | 76.6 | ||||
| Female | 79.7 | 0.791 | |||
| Age | |||||
| <65 | 79.4 | ||||
| ≥65 | 75.7 | 0.323 | |||
| Pathological type | |||||
| Differentiated | 85.2 | 1 | |||
| Undifferentiated | 70.5 | 0.004 | 1.46 | 0.82 to 2.57 | 0.196 |
| Main location | |||||
| Middle or lower | 81.4 | 1 | |||
| Upper | 60.9 | 0.003 | 1.93 | 1.12 to 3.31 | 0.017 |
| Depth of invasion | |||||
| T1 | 96.6 | 1 | |||
| T2-T4 | 61.7 | <0.001 | 6.01 | 2.11 to 17.1 | 0.001 |
| LN metastasis | |||||
| Negative | 95.2 | 1 | |||
| Positive | 54.7 | <0.001 | 6.72 | 2.95 to 15.3 | <0.001 |
| TPX2 | |||||
| Low | 82.8 | 1 | |||
| High | 69.9 | 0.013 | 1.16 | 0.68 to 1.96 | 0.590 |
RFI relapse-free interval, TPX2 targeting protein for Xenopus kinesin-like protein 2, LN lymph node