Table 2.

Summary of validation of inversions predicted in the genome of NA12878 using Valor

Chromosome	Coordinates	Result	InvFEST
chr8	6,922,489–12,573,597	confirmed [51, 52]	HsInv0501
chr15	30,823,312–32,859,062	confirmed [53]	HsInv1049
chr16	16,722,093–18,732,305	confirmed (this study)	HsInv0368
chr17	34,572,064–36,296,916	confirmed (InvFEST)	HsInv1048

Valor returns four coordinates for each inversion for two breakpoints. The coordinates above are the inner breakpoint predictions, and are from the GRCh37 reference genome. The InvFEST database reports inversions in NCBI reference build 36 coordinates, we thus converted the coordinates using the liftOver tool (https://genome.ucsc.edu/cgi-bin/hgLiftOver)