Fig. 1.
Immunohistochemical staining of MRE11 a & b, RAD50 (c & d) and NBS1 (e & f) (20× magnification). a Only complete absence of nuclear staining for MRE11 in tumor cells (⋆) was considered as negative staining. Adjacent normal tissue served as positive internal control (▶). Examples of undetectable RAD50 (c) and NBS1 (e) in tumor cells. Any nuclear staining of MRE11 (b), RAD50 (d) or NBS1 (f) was considered as positive