Fig. 4.

Mouse H2A.L, H2A.B and H2A.P isoforms are expressed in the post-meiotic stages of spermatogenesis. a Expression profile of a selection of H2A.L, H2A.B and H2A.P genes across mouse tissues. All of them are testis-specific. Data were extracted using gene names provided in Table 2 and Additional file 4 from a dataset downloaded from Expression Atlas [87] and published in Ref. [82]. b Expression profiles of a selection of H2A.L, H2A.B and H2A.P genes during mouse spermatogenesis, revealing a maximum expression in the post-meiotic stage. Data have been obtained from Ref. [83]. Lepto leptotene, Zygo zygotene. c Coomassie-stained SDS-PAGE gel loaded with histones extracted from whole testis and elongating spermatids. d Peptides of the mouse H2A.L histone variants identified by mass spectrometry analysis (identified peptides are highlighted in red boxes)