Table 4.

The binding free energies for SEI and ACI complex.

S.no	Anti-ataxia leads	MM P.E. (kcal/mol) (Electrostatic and van der Waal's)	Solvation Energy (kcal/mol)		Free binding energy (kcal/mol)
			Polar	Non-polar	ΔGbinding
1	SEI	−2229.795	560.762	−14.522	−1683.555
2	ACI	−2173.816	595.772	−13.857	−1591.901