Table 2.

Linear regression models of associations between early life socioeconomic status and adult mammographic density, EDMD Study

	Model 1: Adjusted for age at mammogram & adult BMI	Model 2: adjusted, for age at mammogram, adult BMI and early life factors (PTS, birthweight, weight at age 4)	Model 3:adjusted for age at mammogram, adult BMI, early life factors and adult SES (adult education & income)
	β (95% CI)	β (95% CI)	β (95% CI)
Dense area (cm2)
Maternal Education at birth
Less than high school (reference)
High school graduate	0.01 (−4.3, 4.3)	−0.6 (−5.2, 3.9)	−1.7 (−6.3, 3.0)
Trade school or some college	−0.8 (−5.7, 4.2)	−2.9 (−8.0, 2.2)	−4.3 (−9.8, 1.1)
College graduate or higher education	1.8 (−4.4, 8.0)	−1.4 (−8.3, 5.4)	−4.8 (−12.1, 2.4)
Family income at birth
< $5000 (reference)
$5000-$7999	−1.2 (−5.1, 2.7)	−1.4 (−5.4, 2.6)	−1.5 (−5.7, 2.7)
≥ $8000	−6.3 (−11.0, −1.6)	−6.9 (−11.8, −2.1)	−8.2 (−13.3, −3.2)
Non-dense area (cm2)
Maternal education at birth
Less than high school (reference)
High school graduate	−7.7 (−18.0, 2.6)	−5.4 (−15.6, 4.8)	−5.7 (−16.5, 5.0)
Trade school or some college	−1.0 (−13.4, 11.4)	−3.3 (−16.1, 9.6)	−3.8 (−17.0, 9.4)
College graduate or higher education	−8.2 (−20.8, 4.4)	−5.5 (−19.2, 8.3)	−3.5 (−18.6, 11.5)
Family income at birth
< $5000 (reference)
$5000-$7999	−4.3 (−13.2, 4.6)	−3.6 (−12.4, 5.2)	−1.9 (−11.1, 7.3)
≥ $8000	−1.9 (−13.2, 9.4)	−1.6 (−13.5, 10.2)	0.8 (−11.4, 12.9)
Percent density
Maternal education at birth
Less than high school (reference)
High school graduate	1.4 (−1.4, 4.2)	0.7 (−2.2, 3.7)	0.4 (−2.6, 3.4)
Trade school or some college	0.5 (−2.8, 3.8)	−0.2 (−3.7, 3.3)	−0.8 (−4.4, 2.9)
College graduate or higher education	4.8 (0.6, 9.1)	3.4 (−1.4, 8.2)	1.1 (−4.0, 6.2)
Family income at birth
< $5000 (reference)
$5000-$7999	−0.7 (−3.2, 1.8)	−0.7 (−3.3, 1.8)	−0.9 (−3.6, 1.8)
≥ $8000	−2.6 (−6.1, 0.9)	−2.3 (−6.0, 1.4)	−3.2 (−6.9, 0.5)

Abbreviations: PTS prenatal tobacco exposure to maternal smoking during pregnancy, BMI Body mass index, CI confidence interval