Table 3.
Univariate and multivariate overall survival (OS) analyses for patients with stage I NSCLC
| Variate | OS rate (%) | Univariate analysis P value |
Multivariate analysis | ||
|---|---|---|---|---|---|
| 3-year | 5-year | HR (95% CI) | P value | ||
| Age (years) | 0.002 | 1.83 (1.26–2.64) | 0.001 | ||
| <60 | 92.6 ± 1.6 | 85.6 ± 2.2 | |||
| ≥60 | 85.8 ± 1.9 | 77.1 ± 2.4 | |||
| Smoking | <0.001 | 1.45 (1.05–2.10) | 0.047 | ||
| Never | 94.1 ± 1.3 | 86.4 ± 2.0 | |||
| Current or ever | 83.4 ± 2.2 | 75.1 ± 2.6 | |||
| BMI | 0.001 | 0.003 | |||
| Underweight | 84.0 ± 5.5 | 75.8 ± 6.7 | 0.012 | 2.24 (1.18–4.25) | 0.013 |
| Normal weight | 84.2 ± 2.4 | 75.5 ± 2.9 | <0.001 | 1.58 (1.07–2.33) | 0.022 |
| Overweight | 94.8 ± 1.3 | 87.7 ± 2.0 | Reference | Reference | Reference |
| Obese | 75.9 ± 7.9 | 65.3 ± 8.9 | 0.002 | 2.87 (1.48–5.59) | 0.002 |
| Extent of resection | <0.001 | 5.01 (2.26–11.07) | <0.001 | ||
| Lobectomy or bilobectomy | 89.6 ± 1.3 | 81.6 ± 1.6 | |||
| Pneumonectomy | 51.3 ± 15.8 | 41.0 ± 15.6 | |||
| Histological differentiation | 0.001 | 0.76 (0.58–0.99) | 0.039 | ||
| Poor | 83.0 ± 2.7 | 73.5 ± 3.2 | |||
| Moderate | 91.5 ± 1.6 | 84.0 ± 2.2 | |||
| Well | 93.2 ± 2.5 | 86.7 ± 3.5 | |||
| T stage | 0.005 | 1.40 (1.08–1.80) | 0.011 | ||
| T1a | 93.8 ± 2.1 | 90.4 ± 2.7 | |||
| T1b | 89.0 ± 3.0 | 82.0 ± 3.8 | |||
| T2a | 87.3 ± 1.8 | 77.3 ± 2.3 | |||
The data of survival rates are expressed as mean ± standard error
HR hazard ratio, CI confidence interval