Figure 7. Mitotic Activity in Cardiomyocytes.
(A) Confocal image depicts proliferating cells phospho-histone H3 (pH3) costained with myosin light chain (MLC) and DAPI. (B) Mitotic activity of endogenous cardiomyocytes (pH3) increased in the border zone in Pim1+ hCSC-injected animals as compared to placebo 8 weeks post-injection (p < 0.05). (C) There were no significant differences in mitotic activity within noncardiomyocyte cells. Scale bar = 20 μm. *p < 0.05 Pim1+ hCSCs vs. placebo. Abbreviations as in Figures 1 and 6.