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. 2016 Nov 1;15(24):3442–3453. doi: 10.1080/15384101.2016.1248006

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© 2016 The Author(s). Published with license by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 7. — Characterization of the persistent subpopulation reveals a non-quiescent state. (A) Distribution of the time to first division of Fucci-red and Fucci-green subpopulations. The Kolmogorov-Smirnov test shows significant difference between the STP duration distributions (time till first division), p < 9e-028. (B) EdU incorporation of the Fucci subpopulations is measured over time. Mean of 2 replicates presented. Error bars: SE. (C) Representative Fucci traces of a STP Fucci-red cell in time-lapse microscopy. (D) Mean of the normalized area increase of STP Fucci-red cells (N = 112). Error bars represent SE.