Figure 3.

Performance comparison of COME and other coding potential calculators. We used the coding potential scores predicted by COME, CNCI, RNAcode, HMMER, CPAT or PhyloCSF to classify lncRNAs from protein coding transcripts in human data. (A) Receiver operating characteristic (ROC) curves of the six coding potential calculators for the T1 test set (mRNA annotation: Gencode; lncRNA annotation: Gencode). (B) AUC values for two test sets, T1 and T2 (mRNA annotation: Refseq; lncRNA annotation: human lincRNA catalog). (C) For the T1 test set, we also show the AUC values for transcripts of differing length.