Figure 4.

Short-range chromatin loops. (A) The distribution of genomic distance between loop anchors. POL2 occupancy in the anchors of RNA POL2 mediated chromatin loops detected by different methods. Red dashed line marks the 8kb distance. (B) CTCF, RAD21 and SMC3 occupancy in the anchors of CTCF mediated short (<8 kb) chromatin loops detected by ChIA-PET2. (C) Example of short chromatin loops near the Myc gene and ChIP-Seq/RNA-Seq signal along the window. PET count number is labelled at the loop. (D) Another example of short chromatin loops near gene TP53I13.