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. Author manuscript; available in PMC: 2017 Jan 10.
Published in final edited form as: Curr Opin Psychiatry. 2012 Mar;25(2):96–102. doi: 10.1097/YCO.0b013e32835035b2

FIGURE 2.

FIGURE 2

Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) outcomes for high-dose D-serine. Baseline (filled bars) and final (open bars) normalized MATRICS domains and overall mean composite (mean T-score of six tested domains) for (a) 30, (b) 60, and (c) 120 mg/kg. (d) Within group effect sizes for each dose. *P <0.05 in a paired t-test between baseline and final (a–c) or in a paired t-test for doses more than 60 mg/kg (d). #Significant (P <0.05) dose by time interaction for 30 vs. 60 mg/kg or more. Reproduced from [29▪].