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. 2015 Sep 9;4(3):400–419. doi: 10.3390/foods4030400

Table 4.

The coded second-order regression coefficients for the encapsulation yield (EY) and the retentions of total saponin (TSC), total phenolic (TPC) and total flavonoid (TFC) content and the total antioxidant activity (TAA) for the bitter melon extract encapsulated powder obtained from the RSM CCD design.

Independent Variables Regression Coefficient Values
EY (Y1) TSC (Y2) TPC(Y3) TFC (Y4) TAA (Y5)
Intercept 63.97 61.58 56.51 50.39 44.33
Linear
X1 5.10 * 5.04 * 9.24 ** 14.66 *** 6.84 *
X2 −6.53 * 4.82 * −1.07 −0.82 0.70
Quadratic
X1 X1 0.87 4.94 12.51 ** 9.53 * 14.01 **
X2 X2 −1.63 4.53 * 16.67 ** 6.81 * 22.48 ***
Interaction
X1X2 4.46 −1.45 −1.51 0.13 −2.69
R2 0.86 0.87 0.98 0.97 0.98
p-value of lack of fit 0.083 0.062 0.071 0.100 0.075

X1: The overall concentration of the encapsulation agents’ stock solution; X2: The ratio of the bitter melon extract to the encapsulation agents’ stock solution; *: p < 0.05; **: p < 0.01; ***: p < 0.0001.