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St3gal2-null mice develop late-onset obesity. (A) Compared to their WT counterparts, 13-month-old St3gal2-null mice are visibly obese. (B) Developmental course of obesity in WT and St3gal2-null mice. Genotypes are significantly different by two-way analysis of variance (ANOVA) with P < 0.001. *P < 0.01 between genotypes by post-hoc Tukey analyses. n = 6–22 mice per group.
