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. 2017 Jan 5;27(2):129–139. doi: 10.1093/glycob/cww098

Fig. 4.

Fig. 4.

St3gal2-null mice display marked insulin resistance. (A) Serum insulin levels are not significantly different between St3gal2-null (null) and WT mice. P = 0.064, n = 15–17 mice per group. (B) Insulin responses of WT and St3gal2-null mice. Insulin was injected intraperitoneally at t = 0 and blood glucose levels measured at indicated times up to 2 h thereafter. Values are expressed as percent difference from the value at t = 0. Genotypes are significantly different by two-way ANOVA (P < 0.001). *P < 0.005 by Tukey post-hoc analyses. n = 5–7 mice per group. (C) Morphometric analyses of β-islet size shows no significant difference between WT and St3gal2-null (null) mice (P = 0.28 by Student's t-test). n = 3 mice per group. Data are from pancreas cross sections (images not shown).