Table I.
Metric | WT | St3gal2-null | Null/WT | P-valueb |
---|---|---|---|---|
Weight (g) | 37.6 ± 0.7 | 45.9 ± 1.0 | 1.22 | <0.001 |
Fat mass (g) | 12.8 ± 0.9 | 19.2 ± 0.5 | 1.50 | <0.005 |
Lean mass (g) | 22.6 ± 0.3 | 24.7 ± 0.7 | 1.09 | <0.05 |
%fat | 34.0 ± 1.9 | 41.9 ± 0.7 | 1.23 | <0.005 |
Fat/lean ratio | 0.57 ± 0.05 | 0.78 ± 0.02 | 1.37 | <0.005 |
VO2 c | 3000 ± 106 | 2560 ± 34 | 0.85 | <0.005 |
VCO2 c | 2960 ± 96 | 2450 ± 44 | 0.96 | <0.001 |
RER | 0.99 ± 0.01 | 0.96 ± 0.01 | 0.97 | <0.02 |
EEc | 15.1 ± 0.5 | 12.8 ± 0.2 | 0.85 | <0.005 |
VO2 d | 4970 ± 93 | 4760 ± 97 | 0.97 | 0.15 |
VCO2 d | 4910 ± 66 | 4570 ± 109 | 0.97 | <0.05 |
RER | 0.99 ± 0.01 | 0.96 ± 0.01 | 0.97 | <0.02 |
EEd | 25.0 ± 0.4 | 23.8 ± 0.5 | 0.95 | 0.10 |
aVO2, oxygen consumption rate (mL/kg/h); VCO2, carbon dioxide production rate (mL/kg/h); RER, respiratory exchange ratio; EE, energy expenditure (kcal/kg/h).
bStudent's t-test, n = 6 per genotype.
cNormalized to kg body weight.
dNormalized to kg lean weight.