Table 1.
Clinical data of pups (P4) born to vaccinated, non-vaccinated (NV) or control mothers.
| Weight (mg) | Length (cm) | Coordination Movement b (cm) | Cutaneous Test c | |
|---|---|---|---|---|
| NV a | 170 ± 0.5 | 5.0 ± 0.1 | 0.2 ± 0.1 | grey-wrinkled |
| gold glyconanoparticles listeriolysin peptide 91–99 (GNP-LLO91–99) | 280 ± 0.4 | 4.0 ± 0.1 | 9.5 ± 0.8 | black-normal |
| gold glyconanoparticles glyceraldehyde-3-phosphate dehydrogenase 1–22 peptide (GNP-GAPDH1–22) | 295 ± 0.5 | 4.2 ± 0.1 | 10 ± 0.7 | black-normal |
| CONTROL | 300 ± 0.5 | 4.0 ± 0.1 | 10 ± 0.8 | black-normal |
a Four groups of pregnant mothers were prepared: non-vaccinated (NV), GNP-LLO91–99-vaccinated, GNP-GAPDH1–22-vaccinated and controls (non-vaccinated). NV and vaccinated groups were challenged with Listeria monocytogenes (LMWT) but not the control group. All P4 pups were examined for clinical data; b Coordination movement test measures in a 10 cm metric paper the length (cm) achieved by each group of mice in 5 min. Results are the mean ±SD of triplicates; c Cutaneous test with magnifying lens to confirm skin color (black, grey or white) and aspect (normal or wrinkled).