Fig. 2. ChIP-seq with valley-finding identifies regions for transcription-factor binding. Genome viewer tracks for Trim27 (chr13:21,267,345-21,277,316), E2f3 (chr13:30,071,171-30,083,320), and Hist1h1b (chr13:21,868,763-21,874,488), showing ChIP-seq reads (top), MACs peaks (middle), valley regions (lower, orange), and IgG control (grey, lower) for H3K27Ac (top 4 rows) and H3K4me3 (bottom 4 rows). The valleys highlight regions where we searched for transcription factor binding motifs.
