| Transforming growth factor beta receptor signaling pathway |
1.27 × 10–12
|
9.29 × 10–11
|
13.76 (20 822; 69; 307; 14) |
Fos, Parp1, Skil, Smad4, Tgfb3, Smad2, Smad9, Ptk2, Smad3, Trp53, Creb1, Jun, Map3k1, Src |
| Negative regulation of cell differentiation |
7.07 × 10–12
|
4.92 × 10–10
|
3.89 (20 822; 610; 307; 35) |
Med1, Hdac2, Vhl, Lmo2, Tcf7l2, Pparg, Hoxa9, Ptk2, Il18, Trp53, Foxo1, Jdp2, Apcs, Pkp2, Xdh, Itgb1, Vim, Ezh2, Erbb2, E2f1, Skil, Erbb4, Myc, Smad3, Hmga2, Meis1, Gsk3b, Itgb1bp1, Mapk1, Pax6, Suz12, Trp73, Ctnnb1, Stat5a, Nfkbia |
| Positive regulation of protein import into nucleus |
8.16 × 10–12
|
5.65 × 10–10
|
3.00 (20 822; 1084; 307; 48) |
Mcph1, Jak2, Med1, Plscr1, Pcna, Bag5, Map2k1, Vhl, Brca1, Pparg, Fadd, Hif1a, Crnkl1, Trp53, Foxo1, Trim28, Mdfi, Traf2, Gch1, Mecom, Atxn3, Ubqln2, Traf6, Atf4, Bag6, Xdh, Nck1, Zbp1, Klf4, Ccr2, Parp1, Skil, Epm2a, Dvl2, Myc, Smad3, Mapk1, Ppp4c, Trp73, Rela, Cd28, Il2ra, Map3k3, Stat5a, Map3k1, Map2k4, Nfkbia, Rab33a |
| Leukocyte homeostasis |
1.50 × 10–11
|
9.76 × 10–10
|
13.16 (20 822; 67; 307; 13) |
Ahr, Sos1, Fas, Lat, Skil, Ppp3cb, Hif1a, Fadd, Casp3, Ikbkb, Il2ra, Stat5a, Mecom |
| Lymphocyte homeostasis |
2.66 × 10–11
|
1.67 × 10–9
|
14.53 (20 822; 56; 307; 12) |
Sos1, Ikbkb, Ahr, Lat, Fas, Il2ra, Skil, Ppp3cb, Stat5a, Fadd, Hif1a, Casp3 |
| Regulation of leukocyte differentiation |
3.73 × 10–10
|
2.05 × 10–8
|
5.75 (20 822; 236; 307; 20) |
Sos1, Fas, Ccr2, Erbb2, Fos, Fadd, Myc,Tal1, Creb1, Gfi1b, Jun, Apcs, Asxl2, Cd28, Il2ra, Ctnnb1, Rb1, Stat5a, Traf6, Tyrobp |
| Regulation of myeloid leukocyte differentiation |
4.13 × 10–10
|
2.24 × 10–8
|
9.13 (20 822; 104; 307;14) |
Fos, Fadd, Myc, Tal1, Creb1, Gfi1b, Jun, Asxl2, Apcs, Ctnnb1, Rb1, Stat5a, Traf6, Tyrobp |
| Hemopoiesis |
7.79 × 10–10
|
4.16 × 10–8
|
8.71 (20 822; 109; 307; 14) |
Jak2, Med1, Klf4, Ahr, Ccr2, Lmo2, Hif1a, Hoxa9, Meis1, Tal1, Sox6, Ctnnb1, Sp3, Sp1 |
| Positive regulation of chromosome organization |
4.45 × 10–9
|
2.13 × 10–7
|
8.48 (20 822; 104; 307; 13) |
Brca1, Smad4, Eed, Trp53, Tal1, Plk1, Ctbp1, Jdp2, Gfi1b, Asxl2, Ctnnb1, Rb1, Ep300 |
| Positive regulation of myeloid leukocyte differentiation |
7.35 × 10–8
|
3.06 × 10–6
|
11.52 (20 822; 53; 307; 9) |
Gfi1b, Jun, Fos, Asxl2, Rb1, Stat5a, Fadd, Traf6, Creb1 |
| Positive regulation of cytokine production |
7.47 × 10–8
|
3.10 × 10–6
|
4.21 (20 822; 322; 307; 20) |
Jak2, 2Atp6ap2, Ccr2, Brca1, Fadd, Hif1a, Smad3, Il18, Creb1, Rela, Cd28, Rel, Traf2, Stat5a, Arnt, Hdac1, Traf6, Src, Atf4, |
| Regulation of apoptotic signaling pathway |
1.16 × 10–6
|
3.79 × 10–5
|
5.31 (20 822; 166; 307; 13) |
Jak2, Plscr1, Nck1, Fas, Skil, Fadd, Mapk8, Smad3, Myc, Trp53, Gsk3b, Trp73, Traf2 |
| Myeloid cell development |
4.62 × 10–6
|
1.31 × 10–4
|
10.32 (20 822; 46; 307; 7) |
Sox6, Med1, Ptpn11, Tal1, Meis1, Ep300, Src |
| Positive regulation of lymphocyte proliferation |
7.38 × 10–6
|
1.97 × 10–4
|
5.95 (20 822; 114; 307; 10) |
Nck1, Ccr2, Cdkn1a, Cd28, Stat5a, Fadd, Traf6 |
| Regulation of Wnt signaling pathway |
3.49 × 10–5
|
7.84 × 10–4
|
3.88 (20 810; 227; 307; 13) |
Hdac2, Cdh1, Atp6ap2, Tcf7l2, Dvl2, Smad3, Dkk3 Dvl1, Foxo1, Mdfi, Hdac1, Src, Xiap |
