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. 2017 Jan 10;14(1):e1002212. doi: 10.1371/journal.pmed.1002212

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© 2017 Hoglund et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — k_TR is the absorption transit rate constant. CL is the elimination clearance. V_C is the volume of distribution of the central compartment. V_P1 and V_P2 are the volumes of distribution of the first and second peripheral compartments, respectively. Q₁ and Q₂ are the inter-compartment clearances for the first and second peripheral compartments, respectively. F is the relative oral bioavailability.