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. 2017 Jan 10;12(1):e0169609. doi: 10.1371/journal.pone.0169609

Fig 1. SDF-1α-induced platelet aggregation via CXCR4 and PI3 kinase.

Fig 1

(A) Data on platelet aggregation analyzed using platelet-rich plasma. Platelets were stimulated with 100 ng/ml, 250 ng/ml, and 1 μg/ml SDF-1α. (B) 1 μg/ml SDF-1α–induced platelet aggregation with or without pretreatment with 5 μg/ml AMD3100 for 10 min, (C) 1 μg/ml SDF-1α-induced platelet aggregation with or without pretreatment with 30 μM LY294002 for 10 min. Platelet aggregation was measured turbidimetrically using a platelet aggregometer (NBS HEMA TRACER 601) (1 donor, n = 3). Bars represent 1 min. Arrows indicate the time of SDF-1α injection.