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Brouet reclassification.
| Type | I | II | III |
|---|---|---|---|
| Frequency | 25–30% | 25% | 50% |
| Clonality | Monoclonal Ig | One or more monoclonal Igs + polyclonal Igs | Polyclonal Igs Oligoclonal Igs + polyclonal Igs (microheterogeneous) |
| Immunoglobulin Classes | IgM (most abundant) IgG (IgG2, IgG3) IgA (rarely) FLCs |
IgM vs IgG IgG vs IgG IgA vs IgG (rarely) |
IgM-IgG IgM-IgG-IgA IgG-IgA-FLCs |
Modified from Passerini G. et al.16 Abbreviation: Ig: Immunoglobulin; FLCs: Free Light Chains.
