Table 1.
List of screened drugs and compounds
| Anticonvulsants | Cholinergic | Glutamate | Dopamine | Chloride | Antiinflammatory |
| Carbamazepine | Amantadine HCl | ACPD | Clomipramine | Acetazolamide | Carprofen |
| Diazepam | Atropine sulfate | CPPG | Dopamine HCl | Bumetanide | Celecoxib |
| Ethosuximide | Carbachol | DCG IV | Haloperidol | Chlorothiazide | Celecoxib + |
| Felbamate | Diphenhydramine | Dextromethorphan | CLP257* | Phenytoin | |
| Gabapentin | Edrophonium | HBr | Serotonin | D4.2* | Deracoxib |
| Levetiracetam (keppra) | Nicotine bitartrate | dL APV | Ketanserin | Furosemide | Diclofenac |
| Phenacemide | Kynurenic acid | Tartrate | IS50699* | Firocoxib | |
| Phenobarbital | Monoamine NT | L‐AP4 | Methysergide | Mannitol | Indomethacin |
| Phenobarbital + | modulators | LY341495 | Zolmitriptan | Ketoprofen | |
| Bumetanide | Amitriptyline | MPEP | Sodium | Ketorolac | |
| Phenytoin | Amoxapine | Opioid | Bretylium Tosylate | LOXBlock‐1* | |
| Pregabalin | Atomoxetine | GABA | Nalbuphine HCl | Digoxin | Meclofenamate |
| Retigabine | Bupropion | Baclofen | Naloxone | Lidocaine HCl | Meloxicam |
| Topiramate | Clonidine | CGP55845 | Tramadol | Tetrodotoxin (TTX) | Piroxicam |
| Valproic acid | Desipramine | Diazepam + CLP257 | TG4‐155* | TTX + Fluoxetine | Rofecoxib |
| Doxepin | Diazepam + IS50699 | TTX + Nortriptyline | Sulindac | ||
| Intracellular signaling | Duloxetine | Flurothyl | Cannabinoid | Zileuton | |
| AG 1024 | Fluoxetine | Gabazine | Rimonobant | Calcium | |
| Akt 1,2 kinase inhibitor | Imipramine | Taurine | Flunarizine | Antioxidant | |
| API‐2 (Triciribine) | Maprotiline | Purine | Verapamil | Acetylcysteine | |
| DFMO | Methylphenidate HCl | Microtubule | Allopurinol | Alpha‐tocopherol | |
| Gefitinib (Iressa) | Modafinil | Colchicine | Caffeine | Potassium | GCEE* |
| K‐252a | Nortriptyline | Vinblastine | Glipizide | ||
| Lyothyronine | Phenelzine | Vincristine | Steroids | Growth factor | |
| PDMP* | Phenelzine + TTX | Dexamethasone | Blinded | Neuregulin‐1* | |
| Picropodophyllotoxin | Propranolol | Antiproliferative | Estradiol | LacCer* | |
| Rapamycin | Reserpine | Carboplatin | Letrozole | LDN‐209884(3‐1)* | Cell death |
| Sildenafil Citrate | Selegiline | Cycloheximide | Lovastatin | LDN‐212320(10‐10)* | Caspase‐3 inhibitor* |
| TGFbeta RI inhibitor* | Sertraline | Etoposide | Megestrol | LDN‐72457(5‐1)* | Erythropoietin |
| TrkB Fc chimera | Venlafaxine | AG 1478 | Tamoxifen citrate | Minocycline |
Drugs marked with an asterisk were obtained from collaborators, while the rest of the drugs were primarily obtained from the NINDS custom compound collection of known bioactives and FDA‐approved drugs.