Table 2.
List of drug‐concentration pairs excluded from analysis due to early toxicity
| Drug name | Concentration | Drug name | Concentration | Drug name | Concentration |
|---|---|---|---|---|---|
| Akt 1/2 kinase inhibitor | 10 μmol/L | Dextromethorphan HBr | 10 μmol/L | Maprotiline | 10 μmol/L |
| Akt 1/2 kinase inhibitor | 5 μmol/L | DFMO | 40 μmol/L | Megestrol acetate | 10 μmol/L |
| Akt 1/2 kinase inhibitor | 2 μmol/L | Diazepam + IS50699 | 1 + 10 μmol/L | Minocycline | 500 μmol/L |
| Alpha‐tocopherol | 10 μmol/L | Duloxetine | 10 μmol/L | Minocycline | 100 μmol/L |
| Alpha‐tocopherol | 1 μmol/L | Erythropoietin | 100 IU/mL | Nortriptyline | 10 μmol/L |
| Alpha‐tocopherol | 0.1 μmol/L | Erythropoietin | 10 IU/mL | Nortriptyline + TTX | 10 μmol/L + 1 μmol/L |
| Amitriptyline | 10 μmol/L | Erythropoietin | 1 IU/mL | Nortriptyline + TTX | 1 μmol/L + 1 μmol/L |
| Amoxapine | 10 μmol/L | Felbamate | 1 μmol/L | PDMP | 50 μmol/L |
| API‐2 (Triciribine) | 10 μmol/L | Flunarizine | 10 μmol/L | PDMP | 25 μmol/L |
| API‐2 (Triciribine) | 5 μmol/L | Fluoxetine | 10 μmol/L | Phenelzine + TTX | 1 μmol/L + 1 μmol/L |
| API‐2 (Triciribine) | 2 μmol/L | Fluoxetine | 2 μmol/L | Phenelzine + TTX | 0.1 μmol/L + 1 μmol/L |
| API‐2 (Triciribine) | 1 μmol/L | Fluoxetine + TTX | 10 μmol/L + 1 μmol/L | Picropodophyllotoxin | 10 μmol/L |
| Bupropion | 10 μmol/L | Gefitinib (Iressa) | 10 μmol/L | Picropodophyllotoxin | 5 μmol/L |
| Caspase‐3 inhibitor | 10 μmol/L | Gefitinib (Iressa) | 1 μmol/L | Picropodophyllotoxin | 2 μmol/L |
| CGP55845 | 1 μmol/L | Gefitinib (Iressa) | 0.1 μmol/L | Picropodophyllotoxin | 1 μmol/L |
| CGP55845 | 0.1 μmol/L | IS50699 | 10 μmol/L | Piroxicam | 10 μmol/L |
| CGP55845 | 0.01 μmol/L | IS50699 | 10 μmol/L | Rimonabant | 10 μmol/L |
| Clomipramine | 10 μmol/L | K‐252a | 1 μmol/L | Sertraline | 10 μmol/L |
| CLP257 | 100 μmol/L | K‐252a | 0.3 μmol/L | Sertraline | 2 μmol/L |
| CLP257 | 100 μmol/L | Ketanserin tartrate | 1 μmol/L | Tamoxifen citrate | 10 μmol/L |
| Colchicine | 1 μmol/L | Ketanserin tartrate | 0.1 μmol/L | TrkB Fc chimera | 1 μg/mL |
| Colchicine | 0.1 μmol/L | Ketanserin tartrate | 0.01 μmol/L | Verapamil | 100 μmol/L |
| Colchicine | 0.1 μmol/L | LacCer | 20 μg/mL | Verapamil | 10 μmol/L |
| D4.2 | 10 μmol/L | LacCer | 10 μg/mL | Vinblastine | 0.1 μmol/L |
| DCG IV | 10 μmol/L | LDN‐212320(10‐10) | 10 μmol/L | Vincristine | 0.1 μmol/L |
| DCG IV | 1 μmol/L | Lidocaine HCl | 10 μmol/L | ||
| Desipramine | 10 μmol/L | Lovastatin | 10 μmol/L |