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PXR enhanced Taxol resistance in A549 cells. (A) The viability of cells was tested by CCK‐8 assay. (B) The proliferation of cells was tested by colony formation assay. (C) The Taxol and 6′‐ hydroxyl Taxol were analyzed by HPLC assay. Data were presented as mean ± SD for three independent experiments. *P < 0.05, **P < 0.01 versus control group and SR12813 + LY335979 group. HPLC, high‐performance liquid chromatography. PXR, pregnane X receptor.
