Fig 1. Subcellular localisation of individually expressed recombinant RdRps from different rabbit caliciviruses.

RK-13 cells were transiently transfected with expression constructs coding for myc-tagged versions of RHDV RdRp (a–c) or RCV RdRp (d–f). Cells were fixed 24 h after transfections and recombinant proteins were immunostained using myc-specific antibodies. Dotted lines indicate the outline of cell nuclei. Percentages indicate frequencies with which different localisation profiles were found (RHDV and RCV RdRp expression was analysed in 1,002 and 820 transfected cells, respectively, obtained from two independent experiments).