Table 1.

Demographics and Age of Alzheimer Disease Onset in Participants With and Without a History of Traumatic Brain Injury

	TBI+ (n=571)			TBI– (n=7054)
	M	SD	Range	M	SD	Range	p
Age of Onset	68.3	10.3	41–102	70.9	9.5	37–103	< .001*
Age of Diagnosis	73.9	10.2	50–102	76.2	9.4	50–104	< .001*
Education	14.5	3.6	0–20	13.8	3.9	0–20	< .001*
Female, n (%)	216	(38)		4136	(59)		< .001*
Caucasian, n (%)	508	(89)		5634	(80)		< .001*
Family History of Dementia, n (%)	309	(54)		3770	(53)		0.76
Heart Attack, n (%)	570	(7)		7029	(6)		0.16
Atrial Fibrillation, n (%)	570	(8)		7022	(7)		0.36
Angioplasty, n (%)	571	(8)		7049	(7)		0.13
Cardiac Bypass, n (%)	571	(5)		7049	(5)		0.17
Pacemaker, n (%)	571	(5)		7053	(4)		0.50
Congestive Heart Failure, n (%)	571	(3)		7040	(3)		0.68
Stroke, n (%)	563	(6)		7026	(6)		0.64
Transient Ischemic Attack, n (%)	566	(7)		7001	(6)		0.52
Hypertension, n (%)	568	(50)		7036	(54)		0.22
Hypercholesterolemia, n (%)	566	(51)		6976	(51)		0.66
Diabetes, n (%)	571	(12)		7038	(13)		0.70
Remote History of Depression, n (%)	565	(21)		6917	(18)		0.07
Recent History of Depression, n (%)	567	(41)		6981	(41)		0.77
APOE ε4 alleles, n (%)							0.43
0 ε4 alleles	158	(41)		1788	(41)
1 ε4 allele	172	(45)		2033	(47)
2 ε4 alleles	56	(14)		537	(12)

Note. * p < .05. n = 7,625. TBI+ = presence of a history of traumatic brain injury with any loss of consciousness and no chronic deficits occurring more than one year prior to the initial visit. TBI– = absence of a history of traumatic brain injury with loss of consciousness. APOE ε4+ = presence of at least one apolipoprotein E-e4 allele. APOE ε4– = absence of an apolipoprotein E-e4 allele.