Table 1.

Interacting surface information of the best docking solutions generated by ClusPro 2.0

Interacting surface information of HSP70 ATP-bound and RAGE
	Interaction energy (kcal/mol)	Interface area A (Å2)	Interface area B (Å2)	No. of interacating residues A	No. of interacting residues B	Salt bridges	Hydrogen bounds	Non-bounded contacts
Mode1.00	−9.44961	914	874	19	23	4	21	135
Mode1.01	−26.4293	1397	1331	26	34	6	19	198
Mode1.02	−11.6721	1136	1084	19	22	8	16	106
Mode1.03	−23.9613	1953	1902	33	43	7	34	243
Mode1.04	−15.463	1187	1222	26	25	7	25	192
Mode1.05	−15.9767	1572	1462	29	29	8	23	194
Mode1.06	−18.2888	1331	1269	24	27	6	14	138
Mode1.07	−15.8098	1338	1194	25	33	5	20	143
Mode1.08	−7.3837	1201	1057	20	26	4	19	156
Mode1.09	−2.42895	1654	1513	25	32	7	21	160
Mean	−14.686	1368.3	1290.8	24.6	29.4	6.2	21.2	166.5

Chain A represents HSP70 ATP-bound (PDB/4B9Q) and chain B represents RAGE in the monomeric form (PDB/3CJJ)