Table 4.

Interacting surface information of the best docking solutions generated by ClusPro 2.0

Interacting surface information of HSP70 ADP-bound and RAGE oligomeric
	Interaction energy (kcal/mol)	Interface area A (Å2)	Interface area B (Å2)	No. of interacting residues A	No. of interacting residues B	Salt bridges	Hydrogen bounds	Non-bounded Contracts
Mode1.00	−18.4109	1610	1684	33	32	10	29	220
Mode1.01	−24.6075	1369	1372	30	26	11	33	186
Mode1.02	−15.4286	1256	1558	25	21	4	19	127
Mode1.03	−16.3374	1340	1203	25	33	4	23	145
Mode1.04	−16.2707	2212	2198	34	48	8	30	306
Mode1.05	−8.83572	1960	1721	28	44	12	32	254
Mode1.06	−9.42297	1834	1826	34	33	10	19	107
Mode1.07	−7.12172	1673	1610	35	31	4	19	157
Mode1.08	−13.2064	1622	1631	27	32	7	20	178
Mode1.09	−11.1987	1686	1670	36	37	4	23	202
Mean	−14.084061	1656.2	1647.3	30.7	33.5	7.4	24.7	188.2

Chain A represents RAGE in the oligomeric form (PDB/4LP5) and chain B represents HSP70 ADP-bound (PDB/2KHO)