Figure 3.

Mean diffusivity (MD) in parcellated cortical regions. The mean diffusivity in parcellated cortical regions with significant difference between Alzhimer's disease (AD) patients and normal controls (NC). Cortical MD of AD patients (solid), amnestic mild cognitive impairment (aMCI) (gray) patietents and NC (blank) are plotted. Stars indicate the significant difference between aMCI patients and NC (p < 0.0005). Pounds indicate the significant differences between aMCI and NC (p < 0.0005). Plus indicate the significant differences between aMCI and AD patients (p < 0.0005). The AAL cortical regions are arranged into temporal (A), frontal (B), occipital (C), parietal (D), and the deep nuclear (E). The regions are numbered according to the anatomical automatic labeling template. Mean diffusivity is given in units of ^*10⁻³ mm²/s.