Table 5.

Voxelwise analysis of variance showing a significant main effect of group, anticipation (gain, loss), and the group x anticipation interaction.

			Center mass MNI Coordinates
Structure	Hemisphere	BA	Volume (μL)	X	Y	Z	mean F	mean Hedge's g
Group
Caudate/Medial Frontal Gyrus/Posterior Cingulate	L	24/23	52,947	−8	10	21	6.4	0.8
Thalamus/Posterior Insula	L	13	8,937	−27	−32	6	6.3	0.8
Inferior Parietal Lobule	L	40	8,532	−33	−42	53	6.2	0.8
Postcentral Gyrus/Inferior Parietal Lobule	R	2/40	6,750	47	−28	40	6.3	0.8
Superior Temporal Gyrus	L	37	3,672	−45	−49	11	6.7	0.8
Anterior Insula	R	13	3,537	35	3	1	5.5	0.7
Lingual Gyrus	R	18	3,348	2	−77	1	6.0	0.8
Superior Frontal Gyrus	R	9	3,024	34	34	35	6.9	0.8
Precentral Gyrus	R	6	2,187	29	−15	61	5.9	0.8
Anticipation
Medial Frontal Gyrus	L	9	2,187	−7	43	17	5.7	0.7
Precentral Gyrus	R	6	2,025	41	11	40	6.9	0.8
Inferior Frontal Gyrus	L	45	1,755	−40	30	0	5.4	0.7
Group x Anticipation
Middle Frontal Gyrus	L	9	4,968	−35	28	11	5.7	0.7
Medial Frontal Gyrus	L	24	4,887	−6	42	18	5.9	0.8
Inferior Frontal Gyrus	L	44	3,483	−43	7	22	6.0	0.8
Inferior Parietal Lobule	L	40	2,214	−59	−32	33	6.1	0.8
Supramarginal Gyrus	R	40	1,890	34	−38	37	5.7	0.7
Superior Parietal Lobule	L	7	1,728	−26	−58	48	5.1	0.7

Note: Coordinates are in RAI format. BA: Brodmann's area; METH−: healthy comparison participants; METH+: participants with a history of methamphetamine dependence.