Table 1.
Description of data from all children (n = 102), and the subgroup of children with epilepsy (n = 88)
| Variable | All children (n = 102), number (%)/median (IQR) | Children with epilepsy (n = 88), number (%)/median (IQR) |
|---|---|---|
| Gender male | 53 (52) | 46 (52) |
| Age at cognitive testing (years) | 8.2 (4.7–12.0) | 8.0 (4.0–11.9) |
| Intelligence equivalent (IE) | 59 (39–78) | 55 (30–73) |
| Mutation | ||
| TSC1 | 27 (27) | 21 (24) |
| TSC2 | 67 (66) | 60 (68) |
| NMI | 6 (6) | 5 (6) |
| Epilepsy | 88 (86) | 88 (100) |
| Infantile spasms | 37 (36) | 37 (42) |
| Age at seizure onset (months) | 8 (4–24) | 6 (3–16) |
| Number of AEDs used | 1 (0–3) | 2 (1–4) |
| Success of first AED | 75 (74) | 61 (70) |
| Vigabatrin used | ||
| First AED | 33 (32) | 19 (22) |
| Second AED or later | 30 (29) | 30 (34) |
| Never used | 39 (38) | 39 (44) |
| Corticosteroid treatment | 5 (5) | 5 (6) |
| Age of walking independently (months) | 18 (14–22) | 18 (14–23) |
IQR inter quartile range, NMI no mutation identified, AED anti-epileptic drug