Table 2.
Variable | Univariable β | 95% CI | p value | Multivariable β | 95% CI | p value |
---|---|---|---|---|---|---|
Mutation | ||||||
TSC1 | 17.7 | −2.0 to 37.4 | 0.078 | 5.7 | −12.3 to 23.7 | 0.534 |
TSC2 | −3.3 | −21.6 to 15.1 | 0.728 | −3.5 | −20.3 to 13.2 | 0.679 |
Epilepsy | −28.4 | −42.3 to −14.6 | 0.000 | −8.8 | −28.5 to 10.9 | 0.383 |
Infantile spasms | −18.3 | −28.4 to −8.2 | 0.000 | 2.0 | −10.0 to 13.9 | 0.746 |
Age at seizure onset (months) | 1.7 | 1.3 to 2.2 | 0.000 | 1.2 | 0.4 to 2.0 | 0.005 |
Number of AEDs used | −6.3 | −8.6 to −4.0 | 0.000 | −0.9 | −4.7 to 2.9 | 0.634 |
Success of first AED | 15.7 | 4.0 to 27.4 | 0.008 | −0.2 | −12.3 to 11.8 | 0.972 |
Vigabatrin used | ||||||
First AED | −0.9 | −12.9 to 11.1 | 0.881 | −3.3 | −17.7 to 11.1 | 0.654 |
Second AED or later | −14.6 | −26.9 to −2.3 | 0.020 | −4.5 | −17.8 to 8.8 | 0.509 |
Never used | x | x | x | x | x | x |
Corticosteroid treatment | −33.2 | −56.1 to −10.3 | 0.005 | −11.8 | −34.9 to 11.3 | 0.318 |
Age of walking independently (months) | −2.1 | −3.2 to −0.9 | 0.000 | −0.3 | −1.5 to 0.9 | 0.622 |
CI confidence interval, AED anti-epileptic drug