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. 2016 Nov 21;79(1):17–27. doi: 10.1007/s00280-016-3189-1

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Waterfall plot for evaluable patients: best change from baseline in target lesions sum of diameters (%) and best confirmed overall response (RECIST version 1.0). ^aBest response was unconfirmed partial response, where subsequent measurements were non-confirmatory.^bThis patient had CR in the target lesion but progressive disease in nontarget lesions; best overall response of SD was observed at the previous assessment. CUP cancer of unknown primary