Table 2.
Effect of age, stress and mood on resting-state default mode network connectivity (multiple regressions, corrected for multiple comparisons, p < 0.05)
| Effect | Correlation | Regions | Peak MNI coordinates | Cluster size (voxels) | Maximum Z score |
|---|---|---|---|---|---|
| Age | Negative | Anterior cingulate cortex (right) | 3, 42, 3 | 601 | 3.98 |
| Frontal medial orbitofrontal cortex (right) | 3, 54, 0 | 3.41 | |||
| Precuneus (right) | 12, −63, 24 | 145 | 3.61 | ||
| PSS | Positive | Frontal superior gyrus (left) | −21, 39, 42 | 63 | 3.34 |
| Frontal middle gyrus (right) | 30, 36, 45 | 52 | 3.25 | ||
| Middle cingulate gyrus (left) | −12, −45, 33 | 87 | 2.94 | ||
| Posterior cingulate gyrus (right) | 6, −39, 30 | 2.87 | |||
| Precuneus (right) | 12, −45, 6 | 63 | 2.68 | ||
| Occipital middle gyrus (left) | −36, −87, 27 | 68 | 2.57 | ||
| Frontal medial orbitofrontal cortex (left) | −3, −51, −3 | 52 | 2.55 | ||
| GDS | Negative | Frontal middle gyrus (right) | 27, 39, 42 | 69 | 3.68 |
| Cuneus (left) | −6, −66, 24 | 59 | 3.29 | ||
| Calcarine (left) | −9, −63, 15 | 2.61 | |||
| Frontal medial orbitofrontal cortex (left) | −3, 60, −9 | 154 | 2.66 | ||
| Anterior cingulate cortex (left) | −3, 54, 0 | 2.64 | |||
| Frontal medial orbitofrontal cortex (right) | 9, 39, −6 | 2.60 | |||
| Parietal inferior lobule (right) | 57, −60, 42 | 2.59 | |||
| Frontal middle gyrus (right) | 39, 15, 60 | 60 | 3.09 | ||
| Frontal middle gyrus (left) | −36, 15, 39 | 55 | 2.99 |