Table 1.
Demographic Characteristics at Enrollment in the Total Vaccinated Cohort, Overall and by Vaccine Formulation Received or Control Group
| Characteristic | 10 µg RSV-PreF |
30 µg RSV-PreF |
60 µg RSV-PreF |
Controla 1 (n = 17) |
Controla 2 (n = 16) |
Overall (n = 128) |
|||
|---|---|---|---|---|---|---|---|---|---|
| Without Alum (n = 16) | With Alum (n = 16) | Without Alum (n = 15) | With Alum (n = 16) | Without Alum (n = 16) | With Alum (n = 16) | ||||
| Age at vaccination, y | |||||||||
| Mean ± SD | 32.1 ± 7.8 | 32.1 ± 7.4 | 33.7 ± 6.6 | 32.3 ± 7.2 | 31.1 ± 7.9 | 32.8 ± 6.2 | 30.2 ± 8.7 | 30.8 ± 7.5 | 31.8 ± 7.3 |
| Median (range) | 32.0 (20.0– 43.0) | 32.5 (20.0– 41.0) | 32.0 (21.0– 43.0) | 31.5 (22.0– 44.0) | 30.5 (20.0– 43.0) | 31.0 (21.0– 42.0) | 29.0 (18.0– 45.0) | 32.5 (20.0– 44.0) | 32.0 (18.0– 45.0) |
| Geographic ancestry, no. (%) | |||||||||
| African Heritage/African American | 1 (6.3) | 2 (12.5) | 0 (0.0) | 2 (12.5) | 4 (25.0) | 1 (6.3) | 0 (0.0) | 1 (6.3) | 11 (8.6) |
| American Indian or Alaskan Native | 0 (0.0) | 1 (6.3) | 0 (0.0) | 1 (6.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (1.6) |
| Asian | |||||||||
| Central/South Asian heritage | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| East Asian heritage | 0 (0.0) | 1 (6.3) | 0 (0.0) | 1 (6.3) | 0 (0.0) | 0 (0.0) | 2 (11.8) | 1 (6.3) | 5 (3.9) |
| Japanese heritage | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Southeast Asian heritage | 3 (18.8) | 1 (6.3) | 2 (13.3) | 2 (12.5) | 5 (31.3) | 8 (50.0) | 2 (11.8) | 6 (37.5) | 29 (22.7) |
| Native Hawaiian or Other Pacific Islander | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| White | |||||||||
| Arabic/North African heritage | 1 (6.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (5.9) | 0 (0.0) | 2 (1.6) |
| Caucasian/European heritage | 11 (68.8) | 11 (68.8) | 13 (86.7) | 10 (62.5) | 6 (37.5) | 7 (43.8) | 12 (70.6) | 8 (50.0) | 78 (60.9) |
| Other | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (6.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (0.8) |
Abbreviations: n, number of participants; RSV-PreF, respiratory syncytial virus engineered to preferentially maintain a prefusion conformation; SD, standard deviation; y, years.
a Saccharose NaCl.