Table 1.
Review of English-language literature of metastatic melanoma to the bladder.
| Authors, Journal (year), Pubmed ID | Age and gender | Presenting symptom | Synchronous metastasis | Treatment | Survival |
|---|---|---|---|---|---|
| Amar, Journal of Urology (1964), 14213534 | 33yo Male | Hematuria | Maxillary lesions | Partial cystectomy | NR |
| Bartone, Journal of Urology, (1964), 14118110 | 70yo Female | Hematuria | Lymph nodes | Partial cystectomy | Died within 2 months |
| Weston and Smith, British Journal of Surgery, (1964), 14103391 | 69yo Male | Urinary retention | Widespread | None | Died 5 days after diagnosis |
| Dasgupta and Grabstald, Journal of Urology (1965), 14290417 | 2 patients A. 35yo Male B. 35yo Female |
A. Hematuria B. Hematuria |
A. Axillary lesion B. Inguinal nodes |
A. Transurethral fulguration B. Tumor cryotherapy and partial cystectomy |
A. Died within 4 months B. NR |
| Meyer, Cancer (1974), 4426038 | 3 patients A. 69yo Male B. 60yo Female C. 42yo Male |
A. Incidental B. Hematuria C. Incidental |
A. Widespread B. Unknown C. Lungs |
A. Chemotherapy B. Partial cystectomy C. TUR |
A. NR B. Died 16 months after resection C. Died 2 months after resection |
| Silverstein et al, JAMA (1974), 4408302 | 56yo Male | Hematuria | Lymph nodes | Intratumor injection of BCG vaccine followed by partial cystectomy | Alive at 8 month follow-up |
| Tolley et al, British Journal of Clinical Practice (1975), 1191491 | 48yo Female | Hematuria | Absent | Radical cystectomy | NR |
| Chin et al, Journal of Urology (1982), 7062434 | 70yo Female | Hematuria, voiding, symptoms, suprapubic pain, fatigue | Bowel | Partial cystectomy Colectomy |
NR |
| Stein and Kendall, Journal of Urology (1984), 6387180 | 50yo Male | Hematuria | Absent | TUR chemotherapy | Alive at 2 year follow-up |
| Arapantoni-Dadioti et al, European Journal of Surgical Oncology (1995), 7851567 | 28yo Female | Dysuria | Brain Lungs Lymph nodes |
Incomplete TUR | 2 months after resection |
| Ergen at al, International Journal of Urology & Nephrology (1995), 8775037 | 65yo Male | Hematuria Flank pain |
Renal pelvis Stomach |
Biopsy | Died within 1 week |
| Demiksesen et al, Urologia Internationalis (2000), 10810279 | 45yo Female | Hematuria, urinary frequency | Widespread | TUR chemotherapy | NR |
| Lee et al, Urology (2003), 12893353 | 46yo Male | Hematuria | Widespread | TUR and high-dose IL-2 immunotherapy | NR |
| Martinez-Giron, Cytopathology (2008), 18713248 | 49yo Male | Hematuria | NR | NR | NR |
| Efesoy and Cayan, Medical Oncology (2011), 21042956 | 60yo Female | Hematuria weight loss | Lungs | TUR | Died 7 months after resection |
| Nair et al, Journal of Clinical Oncology (2011), 21189399 | 54yo Male | Hematuria | Widespread including ureteral and renal pelvic tumors | TUR and laser ablation of ureteral and renal pelvic tumors Chemotherapy |
Died within 3 months of TURBT |
| Charfi et al, Case Reports Pathology (2012), 23133774 | 54yo Male | Unknown | Lymph nodes | TUR | Died within 1 month |
| Paterson et al, Central European Journal of Urology (2012), 24578971 | 84yo Male | Incidental | No other metastatic lesions | None | NR |
| Wisenbaugh et al, Current Urology (2012), 24917713 | 4 patients A. 81yo Male B. 84yo Male C. 85yo Male D. 62yo Female |
A. Hematuria and voiding symptoms B. Incidental C. Hematuria D. Incidental |
A. Solidary B. Small bowel C. Widespread D. Lymph node small bowel widespread |
A. TUR B. TUR C. TUR D. TUR |
A. Alive at 10 months B. Died at 4 months C. Died within 4 months D. Died within 5 months |
| Rishi et al, International Journal of Surgical Pathology (2014), 23794493 | 61yo Female | Hematuria dysuria |
Brain Lung Skin |
TUR Brain radiotherapy High-dose interferon Temozolomide |
Died with 2 months |
| Meunier et al, Case Reports Pathology (2015), 26106499 | 55yo Female | Hematuria | Liver Spleen Lung |
Checkpoint inhibitor | NR |
| Shukla et al, Journal Endourology Case Reports (2016), 27579421 | 60yo Male | Hematuria | Widespread | TUR | Alive at 1 year follow-up |
| Current report | 49yo Female | Hematuria | Brain | Brain SBRT, checkpoint inhibitors | - |
TUR–transurethral resection; SBRT–stereotactic body radiotherapy; NR–not reported.