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Sensitivity of IHC and MSI PCR
| Screening method | True MSI-H | True MSS |
|---|---|---|
| IHC | ||
| IHC-deficient | 18 | 0 |
| IHC-intact | 1 | 59 |
| IHC sensitivity | 18/(18 + 1) = 95% | |
| MSI PCR | ||
| MSI PCR positive | 19 | 0 |
| MSI PCR negative | 0 | 59 |
| MSI PCR sensitivity | 19/19 (100%) | |
IHC, immunohistochemistry analysis; MSI-H, microsatellite instability–high; MSS, microsatellite stable.
