Figure 2.
Cad-11 expression in activated pancreatic stellate cells. A: Immunofluorescence staining of PDAC tissue using anti–α-SMA, Cad-11 antibody, or DAPI. α-SMA (green), Cad-11 (red), and DAPI (blue). Note that Cad-11 can be detected on the membrane of the cancer cells (arrows) and in the α-SMA+, stellate cells (arrowheads). B: Images of PDAC tissue stained in the same way as in A, showing a field predominantly of stellate cells. Note that the α-SMA+, stellate cells also express Cad-11. Original magnification, ×63. Cad-11, cadherin-11; PDAC, pancreatic ductal adenocarcinoma; α-SMA, α-smooth muscle actin.