Table 3. Visual acuity outcomes and mean number of injections in different clinical studies[17].
Author and study | Region | No. of eyes | Mean No. of injections | Mean increase in the number of ETDRS letters over one year |
CATT (Martin et al, 2012)[14] | Multicentre | 285 | 6.9 | 6.9 |
PrONTO (Philip J. Rosenfeld et al, 2009)[15] | America | 40 | 5.6 | 5.6 |
Muniraju et al, 2013 [17] | Britain | 174 | 4.8 | 3.0 |
SUSTAIN (Holz et al, 2011)[18] | Multicentre | 513 | 5.6 | 5.6 |
Arias et al, 2011[19] | Spain | 90 | 4.4 | 4.4 |
Bandukwala et al, 2010[20] | Canada | 94 | 5.1 | 5.1 |
Hjelmqvist et al, 2011[21] | Sweden | 370 | 4.7 | 4.7 |
Kumar et al, 2011[22] | Britain | 81 | 5.6 | 5.6 |
Williams and Blyth, 2011[23] | Britain | 615 | 5.6 | 5.6 |
Present study | China | 91 | 5.1 | 7.4 |