Table 3. Histological data and univariate analysis of overall survival.
| n (%) | Median OS, months (95% CI) | P value | |
|---|---|---|---|
| Morphological size (n = 82) | 0.79 | ||
| Small cell | 34 (41) | 16 (8.5–23.5) | |
| Large cell | 48 (59) | 15 (13.0–17.0) | |
| Synaptophysin staining (n = 81) | 0.12 | ||
| Positive | 79 (98) | 16 (13.5–18.5) | |
| Negative | 2 (2) | 6 (−) | |
| CgA staining (n = 92) | 0.97 | ||
| Positive | 66 (72) | 16 (12.8–19.2) | |
| Negative | 26 (28) | 13 (10.6–15.4) | |
| Ki-67 (n = 89)a | 70 (20–100) | — | 0.58 |
| <55% | 23 (26) | 22 (10.2–33.8) | 0.06 |
| ≥55% | 66 (74) | 14 (12.0–16.0) | |
| Presence of necrosis (n = 58) | 0.08 | ||
| Yes | 50 (86) | 14 (11.0–17.0) | |
| No | 8 (14) | Not reached |
Abbreviations: CgA, chromogranin A; CI, confidence interval; OS, overall survival; Notes: aMedian (range).