Table 1.
Demography and baseline characteristics (ITT population, N = 76)
| Mean (SD), N = 76 | ||
| Age at informed consent, years | 64.80 (8.39) | |
| Height, cm | 168.22 (8.55) | |
| Weight, kg | 75.45 (15.52) | |
| BMI, kg/m2 | 26.65 (5.05) | |
| Smoking history Number of pack-years, years |
50.13 (23.28) | |
| Years since COPD diagnosis | 5.17 (5.24) | |
| Age at COPD diagnosis, years | 60.16 (10.96) | |
| FEV1 % predicted | 56.09 (13.28) | |
| FEV1*, L | 1.50 (0.45) | |
| FVC*, L | 2.95 (0.89) | |
| IC, L | 2.45 (0.69) | |
| Total Lung Capacity (TLC), L | 7.13 (1.42) | |
| TLC % of predicted normal value | 120.68 (18.75) | |
| Airway Resistance (Raw) | 6.73 (3.19) | |
| Raw % of predicted normal value | 210.99 (117.11) | |
| Hyperinflation IC/TLC | 0.35 (0.09) | |
| N (%) | ||
| Gender | Male | 45 (59.2) |
| Female | 31 (40.8) | |
| Number of patients with current medical condition | CAD | 7 (9.2) |
| Hypertension | 29 (38.2) | |
| Diabetes mellitus | 4 (5.3) | |
| Number of patients according COPD GOLD-stage | Stage I | 8 (10.5) |
| Stage II | 31 (40.8) | |
| Stage III | 30 (39.5) | |
| Stage IV | 7 (9.2) | |
ITT intention to treat, N/n number of patients, BMI body mass index, SD standard deviation, COPD chronic obstructive pulmonary disease, FEV 1 forced expiratory volume in 1 s, FVC forced vital capacity, IC inspiratory capacity, CAD coronary artery disease, GOLD stage defined as: stage I = FEV1/FVC <70% and FEV1 ≥80% predicted; stage II = FEV1/FVC <70% and 50% ≤FEV1 <80% predicted; stage III = FEV1/FVC <70% and 30% ≤FEV1 <50% predicted; stage IV = FEV1/FVC <70% and FEV1 <30% predicted
* N = 75